Services
EBOO Therapy
Introducing EBOO
By Dr Gerard Thomas, Oxyzone
At Oxyzone, we are committed to bringing our patients the most advanced and effective ozone-based therapies available. It is with great excitement that I introduce EBOO Therapy - Extracorporeal Blood Oxygenation and Ozonation – a cutting-edge treatment now offered at our rooms.
EBOO represents one of the most sophisticated forms of intravenous ozone therapy currently available worldwide. The process involves circulating a patient’s blood through a specialised system where it is gently infused with a carefully measured blend of oxygen and ozone, while at the same time being filtered to remove impurities. This dual action both enriches the blood with oxygen and reduces the toxic load, allowing the body to function with greater efficiency and resilience.
Unlike traditional ozone therapies, which are administered in shorter sessions, EBOO provides a continuous flow of oxygen-ozone into the bloodstream, ensuring deeper penetration and broader systemic benefits. Many patients struggling with the lingering effects of chronic illness, fatigue, or toxin exposure are already reporting improved recovery, increased energy, and better overall wellbeing following treatment.
South Africa is still in the early stages of adopting this remarkable therapy, and Oxyzone is proud to be among the first centres in the country to make EBOO available. By combining advanced medical technology with the proven benefits of ozone, we are able to offer patients a new avenue for healing, one that complements and enhances other integrative approaches to health.
At its core, EBOO therapy is about restoring balance to the body – supporting circulation, oxygen delivery, and detoxification – so that healing can happen naturally. For patients seeking safe, innovative options for chronic conditions or recovery, I believe this therapy represents an important step forward in holistic healthcare.
How does it work?
The EBOO process is similar in principle to dialysis, although it is designed specifically for oxygenation and detoxification. A typical session involves several key steps:
Blood Extraction:
A small amount of blood is gently drawn from one arm through an intravenous line.
Filtration:
Over the course of the treatment, two to three litres of blood are circulated through a specialised filter. This helps remove harmful substances such as biofilms, microclots, pathogens, toxins, microplastics, and even viral spike proteins, all of which can place strain on the body.
Oxygenation and ozonation:
Over the course of the treatment, two to three litres of blood are circulated through a specialised filter. This helps remove harmful substances such as biofilms, microclots, pathogens, toxins, microplastics, and even viral spike proteins, all of which can place strain on the body.
Reintroduction:
The freshly purified and oxygen-rich blood is then returned to the body through another IV line. Patients often describe feeling lighter, clearer, and more energised as a result.
A complete EBOO session usually takes around 60 minutes. During this time, patients are comfortably seated and able to relax while the therapy works to cleanse, oxygenate, and restore balance to the body.
The Benefits
EBOO therapy is one of the most advanced ozone-based treatments available, and its impact on health can be far-reaching. By combining detoxification with enhanced oxygen delivery, the therapy supports the body in multiple ways.
One of the most important benefits is immune system support. By stimulating and balancing immune responses, EBOO helps the body defend itself more effectively against infections and chronic illness. At the same time, the process of detoxification assists in removing harmful substances such as heavy metals, environmental toxins, pathogens, and viral spike proteins. This reduces the overall toxic burden on the body, allowing its natural healing systems to function more efficiently.
EBOO therapy also addresses one of the root causes of many chronic health problems: inflammation. By reducing persistent inflammation, patients may experience relief from symptoms linked to autoimmune conditions, cardiovascular issues, and other long-term illnesses. Improved circulation and oxygen delivery further enhance this effect, ensuring that tissues receive the nutrients and energy they need for recovery.
For many patients, one of the most noticeable outcomes is a boost in energy levels. By increasing the production of ATP – the body’s cellular “fuel” – EBOO helps combat fatigue and promotes vitality. This often goes hand in hand with improved mental clarity, reduced brain fog, and sharper cognitive function.
Beyond these immediate benefits, EBOO therapy also plays a role in pain reduction and tissue regeneration. Patients with chronic pain often report significant improvements, while the oxygen-rich environment created by the therapy encourages healing and repair at a cellular level.
In essence, EBOO therapy works on multiple fronts: it strengthens the immune system, cleanses the body of harmful toxins, restores balance to inflammation, boosts energy, and promotes regeneration. For patients seeking a comprehensive approach to improved health and wellbeing, EBOO offers a powerful and promising solution.
Why is EBOO Superior?
Why is EBOO Superior to Other IV Ozone Therapies?
EBOO therapy stands apart from other intravenous ozone options because of its unique design, which functions in a way similar to dialysis. Unlike standard ozone treatments that provide short infusions, EBOO works continuously and at a much greater volume, offering deeper and more comprehensive benefits.
During a typical session, two to three litres of blood are gently circulated through the EBOO system. As this happens, two key processes take place simultaneously:
Ozonation: The blood is infused with a carefully balanced oxygen–ozone mixture before being returned to the body. This process stimulates natural healing mechanisms at the cellular level, helping the body use oxygen more efficiently. Patients may experience reduced inflammation, improved energy production, elimination of harmful microbes, and a reduction in free radical damage.
Detoxification and filtration: At the same time, the blood is passed through a specialised filtration system that removes harmful substances such as toxins, biofilms, microclots, microplastics, heavy metals, and pathogens. This dual approach means that the blood returning to the body is both purified and oxygen-rich, offering a level of therapeutic benefit that other IV ozone methods cannot match.
Emerging evidence also suggests that EBOO may help reduce viral spike proteins and other toxin-like compounds in the bloodstream, which are increasingly linked to lingering symptoms after Covid-19. For patients struggling with post-viral syndromes, this makes EBOO a particularly promising treatment option.
By combining continuous ozonation with advanced filtration, EBOO provides a more powerful and effective form of ozone therapy — supporting detoxification, immune balance, and deep cellular healing in a single session.
Extracorporeal Blood Oxygenation Ozonation & Filtration
EBOO/F, which stands for Extracorporeal Blood Oxygenation, Ozonation and Filtration, is the most advanced form of intravenous ozone therapy currently available. What makes this treatment unique is its dual action: while two to three litres of blood are circulated through a specialised medical system, they are simultaneously enriched with a carefully measured oxygen–ozone blend and purified through high-grade filtration. This ensures not only enhanced oxygen delivery but also the removal of harmful substances such as toxins, microclots, and pathogens.
Like other forms of IV ozone therapy, EBOO/F improves oxygen utilisation, stimulates the body’s natural healing mechanisms, strengthens immunity, and assists in controlling infections. However, EBOO/F is the only method that combines these effects with active blood filtration, giving it a broader and more powerful therapeutic impact. At Oxyzone, we have invested in advanced technology to ensure that every treatment is delivered with the highest standards of safety and efficacy.
The health benefits of EBOO/F therapy are wide-ranging. Patients often experience improvements in:
- Tissue regeneration and healing
- Immune system support and resilience
- Pain reduction in chronic conditions
- Pathogen elimination including bacterial and viral load reduction
- Reduced inflammation, a key driver of chronic disease
- Enhanced detoxification of toxins and environmental stressors
- Improved circulation and oxygen delivery to tissues
EBOO/F therapy at Oxyzone is carefully supervised and individually tailored to each patient’s needs. My approach is to work closely with patients to align treatment with their health goals, while ensuring that safety and comfort remain at the centre of care. By integrating this advanced therapy into our holistic medical practice, we aim to offer patients an effective and innovative path to recovery, resilience, and long-term wellbeing.
Who can benefit?
Chronic Illness
Patients living with chronic illness often benefit greatly from EBOO. Conditions such as autoimmune disorders, cardiovascular disease, and long-standing fatigue syndromes are frequently linked to poor circulation, high levels of inflammation, and toxic overload. By cleansing the blood and improving oxygen delivery, EBOO creates the conditions for the body to recover more effectively.
Infections, Including Long-Covid
Those struggling with the after-effects of infections, including long-Covid, may also find significant relief. The ability of EBOO to reduce viral spike proteins, microclots, and lingering toxins can help restore energy, improve lung function, and reduce the neurological symptoms often described as “brain fog.”
Environmental Toxins
EBOO therapy is also valuable for individuals exposed to environmental toxins or heavy metals through lifestyle, diet, or occupational hazards. By lowering this toxic burden, patients often notice an increase in clarity, stamina, and general wellbeing.
Preventative Care & Wellness
For those seeking preventative care and wellness, EBOO offers a unique advantage. By boosting immune function, supporting healthy circulation, and enhancing cellular energy production, the therapy can help maintain resilience, vitality, and performance even in the absence of chronic illness.
Chronic Pain or Inflammation
Finally, individuals living with chronic pain or inflammatory conditions may experience meaningful improvements. By calming inflammation and improving tissue oxygenation, EBOO supports natural pain relief and tissue repair.
In short, EBOO therapy is not limited to one type of patient. It has the potential to benefit anyone seeking to heal from chronic disease, accelerate recovery, or simply take a proactive step toward better health and longevity.
EBOO is beneficial for Individuals with:
As the most advanced form of IV ozone therapy, EBOO is particularly beneficial for individuals with:
- Chronic illnesses such as chronic fatigue, autoimmune disease, fibromyalgia, diabetes, hepatitis, etc.
- Long Covid-19 and vaccine related injuries
- Cardiovascular conditions – cholesterol disorders, hypertension, cardiovascular disease, peripheral arterial disease.
- Acute and chronic infections – herpes, Lyme disease, EBV, shingles
- Neurological conditions – Parkinson’s disease, dementia, neuropathy
- Inflammatory conditions, chronic pain, and fibromyalgia
- Gastrointestinal conditions – Crohn’s disease, colitis, Celiac disease
- Vaccine injuries
Also a great treatment for individuals seeking:
- Improved energy and vitality
- Stronger immune system and overall wellness enhancement
- Superior athletic recovery and performance
- Patients undergoing detoxification therapies
What does EBOO filter out of my blood?
The EBOO filtration is essential to cleansing your blood of physical debris that neither the kidneys, nor liver, are capable of removing. The purified, debris-free blood is then re-infused back into the patient.
EBOO appears to remove the following from the body:
- Covid-19 spike protein and associated toxin-like peptides
- Heavy Metals – lead, mercury, cadmium, arsenic, etc.
- Extracellular inflammatory fluid
- Endotoxins – which are fragments of pathogenic bacteria, fungus and mold infections that have been killed.
- Biofilms – which is a kind of protective layer that many pathogenic microbes create to hide behind and where our immune cells can not penetrate.
- Debris from our own tissues that have been damaged from the infecting microbes and/or from powerful antimicrobial pharmaceutical drugs.
- Micro clots – microscopic blood clots that are resistant to the body’s own fibrinolytic processes.
- Fungi
- Residuals for medications
- Environmental and industrial toxins – pesticides etc.
- Chemotherapy
- Excessive and/or abnormal blood clotting
- Other impurities
FAQ
EBOO is one of the most effective therapies for eliminating acute and chronic infections, as it exposes the blood to a high concentration of ozone that neutralises bacteria, viruses, fungi, and parasites. What sets it apart is its advanced filtration system, which removes the residual debris often left behind after infections — including endotoxins, biofilms, microclots, and abnormal clotting linked to conditions such as Covid-19 and Chronic Inflammatory Response Syndrome (CIRS). By capturing and clearing what the liver and kidneys cannot efficiently process, EBOO returns purified, oxygen-rich blood to the body, and many patients experience noticeable relief from lingering symptoms soon after treatment.
EBOO is uniquely positioned as a promising therapy for individuals suffering from Long Covid. By targeting multiple proposed root causes of prolonged symptoms, EBOO may offer comprehensive support for recovery. For example, EBOO has the potential to:
- Support the detoxification of Covid-19 spike proteins and toxin-like peptides
- Enhance circulation and aid in the clearance of microclots
- Improve mitochondrial function and cellular energy
- Saturate tissues with oxygen to promote repair and regeneration
- Stimulate the immune system to help eliminate persistent viral reservoirs and co-infections, such as Lyme disease, Epstein-Barr virus (EBV), Mycoplasma pneumonia, and others
Dr. Robin Rose of Terrain Health has been at the forefront of research measuring spike protein and toxin-like peptide levels before and after EBOO treatments. Her preliminary findings show a significant decrease in both markers following treatment. To date, EBOO may be the only therapy demonstrating this level of impact in this area, though further studies are needed to confirm and expand upon these results.
Yes! Ozone therapy is a well-researched, highly effective treatment that addresses root causes of illness with minimal safety risks. It has been extensively studied, with over 2,000 published medical papers supporting its benefits. For more than a century, ozone therapy has been safely and successfully used across Europe, Asia, and Latin America. In the United States, pioneers like Dr. Frank Shallenberger, Dr. Robert Rowen, and the American Academy of Ozonotherapy (AAOT) have advanced this field.
EBOO was invented in the 1980s and has been regularly performed for at least two decades with no published reports of adverse events. There has been major improvements in EBOO technology and we exclusively use the STRATOS EBOO machine which is made in the USA.
As we age or experience illness and toxic exposure, our body’s ability to use oxygen declines. This leads to poor mitochondrial function, reduced antioxidant production, and a buildup of free radicals. Excess free radicals contribute to organ degeneration, weakened immune function, cancer, and other degenerative diseases. Ozone therapy helps counteract these effects by improving oxygen utilization, boosting ATP production, neutralizing free radicals, and protecting organ health. It also strengthens the immune system by stimulating T cell function, helping the body fight infections more effectively.
Dr. Frank Shallenberger says it best, “Since decreased oxygen utilization is the primary cause of degenerative disease, the treatment of all diseases including aging, auto-immune disorders, cancer, cardiovascular disease, etc. is maximally enhanced in the presence of optimal oxygen utilization. This is why ozone therapy can be used in virtually every disease.”
Neurodegenerative conditions such as Parkinson’s disease, Alzheimer’s disease, MS, ALS, and other forms of dementia are complex and often involve multiple underlying factors. Because there is rarely a single cause, the best treatment approach must be personalized for each patient. Contributing factors may include chronic infections, inflammation, toxin buildup, hormone imbalances, genetic predispositions, and nutrient deficiencies. We identify these imbalances through comprehensive blood, urine, and/or stool testing.
EBOO can be a very helpful part of care. It works to improve blood flow, stimulate mitochondrial activity, reduce inflammation, modulate immune function, support detox pathways, and clear infections—including COVID-19 spike protein. Based on our experience and that of our colleagues, EBOO is most effective when combined with a broader, integrative treatment plan rather than used as a stand-alone therapy.
Other therapies we often use alongside EBOO include diet and nutrient therapy, hyperbaric oxygen therapy, deep tissue laser therapy, and biotherapeutic drainage. Together, these approaches address the root causes of neurodegeneration and support the body’s natural healing process.
Some patients report feeling better immediately while others report feeling better 1-2 days after treatment. Please know the ozonides from ozone therapy can persist in the body for 7-10 days, so there are on-going health benefits days after treatment. The benefits of ozone therapy are cumulative, so each additional treatment builds upon the prior treatment and treatment benefit typically lasts longer.
In general we follow these recommendations:
- Patients with chronic illness = once weekly for 3 weeks and reassess. Typically need 4-6 treatments and then only need to return as needed with chronic symptoms flare.
- Patients who are otherwise healthy = 2-4 times per year
- Athletes or those under a lot of physical stress = 4-6 times per year
The number and frequency of treatments you need may vary based on your individual needs and health goals. Some conditions may require more frequent or prolonged treatment, while acute concerns may resolve after just one session.
While EBOO is highly effective, combining it with other naturopathic therapies—such as dietary and lifestyle changes, nutrient supplementation, physical medicine, and herbal medicine—can lead to more significant, long-term results by addressing the root causes of illness.
Yes, you can use a PICC line or a port for the return line only. Additional heparin may be needed to maintain proper flow.
The degree of side effects varies depending on the patient’s individual health, the dose of ozone administered, and the severity of their condition. For example, patients with long-standing chronic illnesses like Long COVID or Lyme disease may experience a “healing reaction” (also known as a Herxheimer reaction or “herx”). This occurs when the immune system is stimulated, detox pathways are activated, and infections begin to die off. As a result, some patients may feel more fatigued immediately after treatment as the body prioritizes healing and recovery.
Other potential side effects may include:
- General IV-related effects such as transient low blood sugar, headache, lightheadedness, local swelling, bruising, or irritation at the catheter insertion site
- A temporary shift in the menstrual cycle
- Slight hemolysis (which may cause brownish or reddish urine)
EBOO & Ozone Therapy is extremely safe when performed by a trained, licensed medical professional using the highest quality equipment. Side effects are rare, but some patients may experience temporary fatigue due to pathogen die-off or the activation of detoxification pathways—both considered positive healing responses.
While ozone therapy is highly safe, it is not suitable for everyone and is contraindicated in individuals with:
- G6PD deficiency
- Pregnancy or lactation
- Uncontrolled hyperthyroidism
- Active bleeding or acute hemorrhagic conditions
- Acute myocardial infarction (heart attack)
- Allergy to heparin
If you have any concerns about whether EBOO is right for you, consult with Dr Thomas to ensure it is a safe and appropriate treatment for your condition.
